'
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.9
USERS' SCORE
Good
Based on 71 Reviews
8.9
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg

Top Medical Research Studies

9
Probiotic improves MS symptoms
The effect of probiotic supplementation on the clinical and para-clinical findings of multiple sclerosis: a randomized clinical trial.
Relevant study on MS treatment
We focused on the effects of the probiotic Saccharomyces boulardii on Multiple Sclerosis (MS) patients, comparing its benefits to a placebo over four months.

Notably, we found that Saccharomyces boulardii significantly lowered inflammatory markers and improved overall antioxidant capacity. Participants also reported less pain and fatigue, alongside enhancements in their quality of life compared to those receiving the placebo.

This suggests that incorporating Saccharomyces boulardii might help alleviate some symptoms related to MS, offering a beneficial avenue for symptom management.
Read More
9
Saccharomyces boulardii prevents IgAN
Saccharomyces boulardii prevents oral-poliovirus vaccine-induced IgA nephropathy in mice.
Indicates probiotic's protective effects
We evaluated how Saccharomyces boulardii affects IgA nephropathy in mice, particularly after an oral poliovirus vaccine (OPV).

The mice were divided into four groups—some receiving the OPV alone, others along with S. boulardii, and a few with just S. boulardii or no treatment.

After six weeks, we found that only the mice receiving the OPV alone showed signs of IgA nephropathy, with increased levels of serum IgA and kidney abnormalities.

In contrast, those treated with S. boulardii or receiving no treatment had normal results.

These findings suggest that S. boulardii can effectively prevent vaccine-induced IgA nephropathy in experimental models.
Read More
8
Saccharomyces boulardii shows potential
Saccharomyces boulardii (CNCM I-745) alleviates collagen-induced arthritis by partially maintaining intestinal mucosal integrity through TLR2/MYD88/NF-κB pathway inhibition.
Relevant for gut inflammation studies
We investigated how Saccharomyces boulardii might help with inflammation in arthritis by focusing on its effects on gut health. Using a rat model of collagen-induced arthritis, we administered S. boulardii alongside Methotrexate for eight weeks.

Our findings highlighted S. boulardii's potential to positively influence gut bacteria, which could be crucial for inflammation management. While the results seem promising, further studies are needed to clearly establish its effectiveness in autoimmune conditions like arthritis.
Read More

Most Useful Reviews

9.5
Reduced inflammation
These capsules significantly reduce inflammation in my gastrointestinal tract, supporting my autoimmunity. They aid nutrient absorption, improve skin health, and overall wellness.
Read More
9.5
Improved digestion
The Tombs of Bulardi Panacea effectively counteracts many "intestinal reptiles" including Candida and assists in normalising stool and digestion. It particularly aids in managing the bacterium Helicobacter, which can trigger gastritis, and boosts immune system function, crucial since 80% of immunity is linked to our intestines. I intend to order this supplement regularly, as it has significantly improved my digestive tract, and I believe I may eventually forget about my autoimmune disorder.
Read More
9.5
C Diff protection
This probiotic is superb for preventing C Diff. My son suffered two episodes after antibiotics, and adding one capsule to his morning smoothie has kept it away ever since. I couldn't be more satisfied.
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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.9
9
Probiotic improves MS symptoms
The effect of probiotic supplementation on the clinical and para-clinical findings of multiple sclerosis: a randomized clinical trial.
Relevant study on MS treatment
We focused on the effects of the probiotic Saccharomyces boulardii on Multiple Sclerosis (MS) patients, comparing its benefits to a placebo over four months.

Notably, we found that Saccharomyces boulardii significantly lowered inflammatory markers and improved overall antioxidant capacity. Participants also reported less pain and fatigue, alongside enhancements in their quality of life compared to those receiving the placebo.

This suggests that incorporating Saccharomyces boulardii might help alleviate some symptoms related to MS, offering a beneficial avenue for symptom management.
Read More
9
Saccharomyces boulardii prevents IgAN
Saccharomyces boulardii prevents oral-poliovirus vaccine-induced IgA nephropathy in mice.
Indicates probiotic's protective effects
We evaluated how Saccharomyces boulardii affects IgA nephropathy in mice, particularly after an oral poliovirus vaccine (OPV).

The mice were divided into four groups—some receiving the OPV alone, others along with S. boulardii, and a few with just S. boulardii or no treatment.

After six weeks, we found that only the mice receiving the OPV alone showed signs of IgA nephropathy, with increased levels of serum IgA and kidney abnormalities.

In contrast, those treated with S. boulardii or receiving no treatment had normal results.

These findings suggest that S. boulardii can effectively prevent vaccine-induced IgA nephropathy in experimental models.
Read More
9
Effective IgA nephropathy treatment method
Yeast Cell Wall-Mediated Ileal Targeted Delivery System for IgA Nepharopathy Therapy.
Highly relevant therapeutic breakthrough
We explored a novel oral drug delivery system designed specifically for treating IgA nephropathy, an autoimmune disorder. Using hydroxychloroquine and dexamethasone paired with yeast cell walls, we aimed for targeted delivery to the ileal region.

Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Read More
9
Yeast polysaccharides may reduce inflammation
Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities.
Highly relevant to autoimmune treatment
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.

MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
Read More
9
Effective anti-BAMBI treatment in mice
Therapeutic Effects of Anti-Bone Morphogenetic Protein and Activin Membrane-Bound Inhibitor Treatment in Psoriasis and Arthritis.
High relevance for autoimmune therapy
We investigated the effects of a novel treatment targeting BAMBI, a protein involved in immune cell regulation, on autoimmune disorders like psoriasis and arthritis in mice. Through careful experimentation with control groups, we found that the anti-BAMBI antibody significantly increased protective Treg cells and reduced disease progression in various models. This treatment effectively prevented skin psoriasis and type II collagen-induced arthritis, hinting at new therapeutic possibilities for chronic inflammatory conditions driven by immune system dysfunction.
Read More

User Reviews

USERS' SCORE
Good
Based on 71 Reviews
8.9
10
Relief from IBS
This product is a miracle for my IBS, inherited from my mother. After taking it, I’ve experienced significant relief from bloating and discomfort, making me feel better than I have in years. I highly recommend it!
10
IBS relief
After suffering IBS for 10 years, this Saccharomyces Boulardii really helped. This formulation is the best I've tried, and the packaging was outstanding.
9.5
Improved bowel function
I have ordered saccharomyces from this company thrice now. I am truly satisfied. After antibiotics, it effectively replenishes intestines with good microflora. My mother had severe bowel issues but now can go to the toilet unaided. I highly recommend this product.
9.5
Candida relief
My favourite remedy! It helped me eliminate thrush within a week. I have not experienced any issues for months. I also bought it for my mother, who has no further complaints after suffering from pain. I highly rate this product for its effectiveness.
9.5
Reduced inflammation
These capsules significantly reduce inflammation in my gastrointestinal tract, supporting my autoimmunity. They aid nutrient absorption, improve skin health, and overall wellness.
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